Michael Matthay, MD

Michael A. Matthay, M.D. is a Professor of Medicine and Anesthesia at the University of California at San Francisco (UCSF), a Senior Associate at the Cardiovascular Research Institute, and Associate Director of the Intensive Care Unit at UCSF. He received his AB from Harvard University and his MD from the University of Pennsylvania. He completed his internal medicine residency training at the University of Colorado. He completed his pulmonary and critical care medicine training at the University of California, San Francisco. He received an American Thoracic Society award for Scientific Achievement in 2002, a UCSF Award for Outstanding Clinical Research in 2006, the Julius Comroe Jr Respiratory Section Award from the American Physiologic Society in 2009, and the UCSF Lifetime Achievement Award for Mentoring in 2013. He is a member of the American Association of Physicians. Dr. Matthay’s basic research has focused on mechanisms of salt, water, and protein transport across the alveolar epithelium that account for the resolution of pulmonary edema. This work led to the development of a method to measure alveolar fluid clearance that has been widely used for basic and clinical studies of lung fluid balance. He has studied the pathogenesis and resolution of acute lung injury and the acute respiratory distress syndrome (ARDS), with an emphasis on translational work and patient-based research, including clinical trials. His recent research has focused on the biology and potential clinical use of allogeneic bone marrow derived mesenchymal stromal cells (MSCs) for ARDS. He is currently leading an NHLBI supported phase 1 and 2 clinical trial of MSCs for ARDS. He has been a dedicated mentor to numerous students, residents and fellows and more than 30 post-doctoral fellows who trained with him have established careers in academic medicine.